HATU

jessie606

HATU nature
Melting point 183-188 °C (dec.)
RTECS No. XZ5633000
Storage conditions 2-8 ° C
Water solubility Soluble in acetonitrile. Insoluble in water.
InChIKey KZAWCZZRROLLDL-UHFFFAOYSA-N
CAS Database 148893-10-1 (CAS DataBase Reference)
EPA Chemical Information 1H-1,2,3-Triazolo[ 4,5-b]pyridinium, 1-[bis(dimethylamino)methylene]-, hexafluorophosphate(1-), 3-oxide(148893-10-1)
HATU uses and synthesis methods
Uses Pharmaceutical intermediates, peptide condensation reagents.
Uses For solid phase peptide synthesis, recent studies have shown that the crystallization or solution of this coupling reagent results in a guanidinium N-oxide rather than a urinary compound.
Peptide coupling reagent; preparation of N-arylsulfonamide-linked polypeptide by solid phase synthesis; recent studies show that the crystal and solution structure of the coupling agent are sulfonium salt N-oxide, not urea cation compound; solid phase peptide Effective coupling agent in synthesis
Security Information
Dangerous goods sign Xi, Xn, E
Hazard Category Code 36/37/38-20/21/22-2
Safety instructions 26-37/39-36/37-36-35
Dangerous goods transport number 1325
WGK Germany 3
F 10-21
HazardClass 4.1
PackingGroup II
Customs code 29339999