2-Aminobenzenesulfonamide

JD008

Chinese name: o-aminobenzenesulfonamide
Chinese synonym: 2-aminobenzenesulfonamide; o-aminobenzenesulfonamide; 2-aminobenzenesulfonamide; o-amine benzenesulfonamide; 2-aminobenzenesulfonamide, 98%; 2-aminobenzenesulfonamide, check; 2-aminobenzenesulfonamide
English name: 2-Aminobenzenesulfonamide
English synonym: 2-amino-benzenesulfonamid; o-amino-benzenesulfonamid; o-aminobenzenesulfonamide; orthanilamide; o-sulfanilamide; o-Aminobenzenesulphonamide; 2-AMINOBENZENESULFONAMIDE; 2-AMINO-BENZENESULFONYL CHLORIDE
CAS No.: 3306-62-5
Molecular formula: C6H8N2O2S
Molecular weight: 172.2
EINECS number: 221-988-1
Related Categories: SULFONAMIDE;Intermediates of Dyes and Pigments;Sulphur Derivatives;Benzene derivates;Organic Building Blocks;Sulfonamides/Sulfinamides;Sulfur Compounds;Nitrogen Compounds;Small Molecule Inhibitors;Inhibitors;Small Molecule Inhibitors,Natural Products

Melting point 155-157 °C (lit.)
CAS Database 3306-62-5 (CAS DataBase Reference)
O-aminobenzenesulfonamide use and synthesis
Chemical Properties Plate or prismatic crystals. Melting point 152-153 ° C. Soluble in ethanol, acetic acid.
Uses Pharmaceutical intermediates for the production of antihypertazines.
Use as medicine, dye intermediate
Production method O-nitrobenzenesulfonamide is obtained by reduction. O-nitrobenzenesulfonamide, hot water, and acetic acid were placed in a reaction tank, and the mixture was stirred and heated to boiling. Iron scraps were added in 6 portions, half an hour apart. The reaction solution is kept boiling while the iron filings are added. Add iron filings and continue to boil for 3h. Filtered while hot, the filter residue is boiled in hot water and filtered. The two filtrates were combined and cooled to crystallize overnight. Filtration and drying gave o-aminobenzenesulfonamide.