Gliclazide 21187-98-4
Price | USD190.00 |
Packge | 1Kg/Bag |
- Min. Order:1KG
- Supply Ability:100KG
- Time:2022-03-18
Product Details
- Product NameGliclazide
- CAS No.21187-98-4
- EINECS No.244-260-5
- MFC15H21N3O3S
- MW323.41
- Appearancepowderwhite
- Melting point 163-169 °C (lit.)
- storage temp. 2-8°C
- density 1.2205 (rough estimate)
Gliclazide is an oral antihyperglycemic agent used for the treatment of diabetes mellitus type II. It belongs to the sulfonylurea class of insulin secretagogues, which stimulates β cells of the pancreas to release insulin. Gliclazide binds to the β cell sulfonyl urea receptor (SUR1), further blocking the ATP sensitive potassium channels. Therefore, the potassium efflux substantially decreases, causing depolarization of the β cells. Then the voltage-dependent calcium channels in the β cell are open, resulting in calmodulin activation, which in turn leads to exocytosis of insulin containing secretorty granules. Recent studies have also shown that gliclazide can effectiveimprove anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes and protect pancreatic beta-cells from damage by hydrogen peroxide.
Company Profile Introduction
Baoji Guokang Bio-Technology Co., Ltd. has a subsidiary, Baoji Guokang Health Chemical Technology Co., Ltd.It is located in Baoji High-tech Zone,with epitomizing international, cooperative and honest. We are a young company full of action and energy, our profession improves us rapid progress, which satisfy our clients both in home and abroad. We are specialized in API's intermediates, fine chemicals and plant extracts.We toughly insist on that quality is always the most important item not only for us, but also for our clients. It is believed that we could be considered as the most powerful man in the area of chemicals with combined strength in R&D and Marketing. We are a "customer first" company and believe that our success depends on double-wins.our customers are from more than 160 countries worldwide ,we work closely with every customer to support high quality business service. Our target purpose is "provide favorable value,convenient and flexible solutions for you."we promise: reasonable prices, short supplying period and satisfactory after-sales service. Buyers are welcome to contact us !
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- Since:2008-05-08
- Address: No.10,the 4th road of High-tech zone, Baoji City, Shaan’xi province, Mainland China