Doxorubicin hydrochloride CAS:25316-40-9
Price | USD95.00 |
Packge | 1g |
- Min. Order:1g
- Supply Ability:100KG
- Time:2022-06-06
Product Details
- Product NameDoxorubicin hydrochloride
- CAS No.25316-40-9
- EINECS No.246-818-3
- MFC27H29NO11.ClH
- MW579.98
- Appearancesolidorange to dark red
- Melting point 216 °C (dec.)(lit.)
- storage temp. 2-8°C
- Water Solubility Soluble in water.
Melting point | 216 °C (dec.)(lit.) |
alpha | D20 +248±2° (c = 0.1 in methanol) |
storage temp. | 2-8°C |
solubility | H2O: 10 mg/mL, clear, red-orange |
pka | pKa 8.25±0.60 (Uncertain);8.43±0.70 (Uncertain);11.9±0.4 (Uncertain);12.95±0.1 (Uncertain);13.8±0.70 (Uncertain) |
form | solid |
color | orange to dark red |
Water Solubility | Soluble in water. |
λmax | 497nm(H2O)(lit.) |
Merck | 14,3439 |
BRN | 4229251 |
Uses | Used as an antineoplastic |
Uses | Strong fluorescent dye intercalating into DNA. Antitumour antibiotic. Effect of adriamycin on heart mitochondrial DNA. Inhibitor of reverse transcriptase and RNA polymerase; immunosuppressive agent. |
Uses | Antibacterial;DNA intercalant |
Uses | Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently. |
Uses | Doxorubicin is an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein.[Cayman Chemical] |
Company Profile Introduction
Baoji Guokang Health Chemical Technology Co., Ltd has a subsidiary, Baoji Guokang Bio-Technology Co., Ltd. It is located in Baoji High-tech Zone,with epitomizing international, cooperative and honest. We are a young company full of action and energy, our profession improves us rapid progress, which satisfy our clients both in home and abroad. We are specialized in API's intermediates, fine chemicals and plant extracts.We toughly insist on that quality is always the most important item not only for us, but also for our clients. It is believed that we could be considered as the most powerful man in the area of chemicals with combined strength in R&D and Marketing. We are a "customer first" company and believe that our success depends on double-wins.our customers are from more than 160 countries worldwide ,we work closely with every customer to support high quality business service. Our target purpose is "provide favorable value,convenient and flexible solutions for you."we promise: reasonable prices, short supplying period and satisfactory after-sales service. Buyers are welcome to contact us !
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- Since:2018-09-06
- Address: Room B801, Financial Plaza, Jintai District, Baoji, Shaanxi, CN