Hydrochlorothiazide CAS 58-93-5

Product Name: Hydrochlorothiazide

CAS: 58-93-5

MF: C7H8ClN3O4S2

MW: 297.74

EINECS: 200-403-3

Overview

Hydrochlorothiazide, also known as hydrochlorothiazide and hydrochlorothiazide, is a thiazide diuretic with moderate diuretic effect. By acting on the cortex of the ascending branch of the medullary loop, it inhibits the active reabsorption of Cl- and the passive absorption of Na+ in this part, thereby diuresis. In addition, this product also has antihypertensive and antidiuretic effects. It is suitable for all kinds of edema, especially cardiogenic edema. It can also be used as an antihypertensive drug for the treatment of mild to moderate hypertension. It also has a certain effect on diabetes insipidus and idiopathic hypercalciuria. Commonly used thiazide diuretics include hydrochlorothiazide, chlorthalidone, indapamide and so on.

Physical and chemical properties

White crystalline powder, odorless, slightly bitter taste. Insoluble in water or chloroform, soluble in acetone, slightly soluble in ethanol, soluble in sodium hydroxide solution, but easy to hydrolyze.