Procaine
| Price | USD50.00 |
| Packge | 1ASSAYS |
- Min. Order:1ASSAYS
- Supply Ability:500
- Time:2022-07-20
Product Details
- Product NameProcaine
- CAS No.59-46-1
- EINECS No.200-426-9
- MFC13H20N2O2
- MW236.31
- AppearanceSolidWhite to Off-White
- Melting point 61°
- Boiling point 378.78°C (rough estimate)
- density 1.0604 (rough estimate)
- Water Solubility 9.45g/L(30 ºC)
- storage temp. Keep in dark place,Sealed in dry,Room Temperature
| Common Name | Procaine | ||
|---|---|---|---|
| CAS Number | 59-46-1 | Molecular Weight | 236.310 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 373.6±22.0 °C at 760 mmHg |
| Molecular Formula | C13H20N2O2 | Melting Point | 61ºC |
| MSDS | N/A | Flash Point | 179.8±22.3 °C |
Use of ProcaineProcaine is a local anesthetic drug of the amino ester group, which acts through multiple targets.Target: OthersProcaine is a local anesthetic of the ester type that has a slow onset and a short duration of action.Procaine (0.01-100 microM) inhibited the 5-HT3 receptor-mediated inward current in the whole-cell patch clamp recording. Procaine appears to produce a competitive inhibition on 5-HT3 receptors with a KD of 1.7 microM [1]. Procaine is a DNA-demethylating agent that produces a 40% reduction in 5-methylcytosine DNA content as determined by high-performance capillary electrophoresis or total DNA enzyme digestion. Procaine can also demethylate densely hypermethylated CpG islands. Procaine also has growth-inhibitory effects in these cancer cells, causing mitotic arrest [2]. Procaine functions as an excitant of limbic system cells, and that procaine alters synaptic transmission in some, but not all, output pathways from the amygdale [3]. |
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