cinchocaine
Price | USD10.00 |
Packge | 1KG |
- Min. Order:1KG
- Supply Ability:20Tons/WEEK
- Time:2021-07-09
Product Details
- Product Namecinchocaine
- CAS No.85-79-0
- EINECS No.201-632-1
- MFC20H29N3O2
- MW343.46
- AppearanceSolid:particulate/powderWhite to yellow
- Melting point 64°
- Boiling point 478.73°C (rough estimate)
- density 1.1145 (rough estimate)
- Water Solubility 68.01mg/L(temperature not stated)
- storage temp. Store at -20°C
Product Description
Product Name | Dibucaine |
Synonyms | Dibucaine Base;Nupercainal;Dibucain;Nupercaine;Dermacaine; Cinchocaine;Cinchocainum;dibucaine;2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide;dibucaine hydrochloride;Dibucaine;Sovcaine;Cincocainio; |
CAS No. | 85-79-0 |
Molecular Formula | C20H29N3O2 |
Molecular Weight | 343.46 |
EINECS No. | 201-632-1 |
Melting point | 64° |
Boiling point | 229.5 °C766 mm Hg(lit.) |
Flash point | 209 °F |
Density | 1.026 g/mL at 25 °C(lit.) |
Refractive index | n20/D 1.501(lit.) |
Appearance | White Powder |
Purity | 99% |
Dibucaine is a local anesthetic of the amide type now generally used for surface anesthesia.Target: Sodium ChannelDibucaine is an amide local anesthetic. Dibucaine reduced the degradation of BSA-gold complex in the reservosomes, which was not caused either by an inhibition of the whole proteolytic activity of the parasite or by a reduction on the expression levels of cruzipain.Dibucaine, a quaternary ammonium compound, inhibited SChE to a minimum within 2 min in a reversible manner. The inhibition was very potent. It had an IC(50) of 5.3 microM with BuTch or 3.8 microM with AcTch. The inhibition was competitive with respect to BuTch with a K(i) of 1.3 microM and a linear-mixed type (competitive/noncompetitive) with respect to AcTch with inhibition constants, K(i) and K(I) of 0.66 and 2.5 microM, respectively. Dibucaine possesses a butoxy side chain that is similar to the butryl group of BuTch and longer by an ethylene group from AcTch.
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- Since:2019-07-05
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