ZM 449829
Synonym(s):(2-Naphthylvinyl Ketone), ZM 449829;JAK3 Inhibitor V - CAS 932258 - Calbiochem
- CAS NO.:4452-06-6
- Empirical Formula: C13H10O
- Molecular Weight: 182.22
- MDL number: MFCD04974535
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:16
What is ZM 449829?
The Uses of ZM 449829
ZM 449829, is a potent, selective inhibitor of JAK3 (Janus tyrosine kinase 3) which binds competitively to the JAK3 ATP site. Also inhibits STAT-5 phosphorylation and T-cell proliferation.
What are the applications of Application
JAK3 Inhibitor V is a selective JAK3 inhibitor
Definition
ChEBI: 1-(2-naphthalenyl)-2-propen-1-one is a member of naphthalenes.
Properties of ZM 449829
Boiling point: | 319.3±15.0 °C(Predicted) |
Density | 1.093±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | White waxy solid |
Safety information for ZM 449829
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 |
GHS Hazard Statements |
H301:Acute toxicity,oral H311:Acute toxicity,dermal H331:Acute toxicity,inhalation H341:Germ cell mutagenicity |
Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P330:Rinse mouth. P361:Remove/Take off immediately all contaminated clothing. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for ZM 449829
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Rimegepant Impurity 3 Ivermectin EP Impurity B Tubulysin C (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin F Tubulysin M Fuel shell 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Calcium Sodium Phosphosilicate IH Imeglimin Hydrochloride IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate Diethyl 2,5-di(furan-2-yl)terephthalate 2-(4-Bromopyridin-2-yl)acetonitrile 1-(4-Chlorophenyl)piperidin-2-one 2-Ethoxy-4-nitrobenzoic acid 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 3-Fluro-6,7-dihydro-5H-Pyrrolo [3,4-b]pyridine dihydro chloride 4-bromo-7H-pyrrolo[2,3-d]pyrimidine 5-bromo-3-iodopyridin-2-olRelated products of tetrahydrofuran
3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE
1,4-CHRYSENEQUINONE
1-(2-NAPHTHYL)-3-(3,4,5-TRIMETHOXYPHENYL)PROP-2-EN-1-ONE
ETHYL 2-(2,6-DIBROMO-4-[3-(2-NAPHTHYL)-3-OXOPROP-1-ENYL]PHENOXY)ACETATE
4'-METHOXY-ALPHA-NAPHTHOFLAVONE
2'-METHOXY-7,8-BENZOFLAVONE
(E)-3-(2-FURYL)-1-(2-NAPHTHYL)-2-PROPEN-1-ONE
1-(2-NAPHTHYL)-3-(2-THIENYL)-2-PROPEN-1-ONE
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