ZM 449829
Synonym(s):(2-Naphthylvinyl Ketone), ZM 449829;JAK3 Inhibitor V - CAS 932258 - Calbiochem
- CAS NO.:4452-06-6
- Empirical Formula: C13H10O
- Molecular Weight: 182.22
- MDL number: MFCD04974535
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is ZM 449829?
The Uses of ZM 449829
ZM 449829, is a potent, selective inhibitor of JAK3 (Janus tyrosine kinase 3) which binds competitively to the JAK3 ATP site. Also inhibits STAT-5 phosphorylation and T-cell proliferation.
What are the applications of Application
JAK3 Inhibitor V is a selective JAK3 inhibitor
Definition
ChEBI: 1-(2-naphthalenyl)-2-propen-1-one is a member of naphthalenes.
Properties of ZM 449829
Boiling point: | 319.3±15.0 °C(Predicted) |
Density | 1.093±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | White waxy solid |
Safety information for ZM 449829
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 |
GHS Hazard Statements |
H301:Acute toxicity,oral H311:Acute toxicity,dermal H331:Acute toxicity,inhalation H341:Germ cell mutagenicity |
Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P330:Rinse mouth. P361:Remove/Take off immediately all contaminated clothing. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for ZM 449829
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE
1,4-CHRYSENEQUINONE
1-(2-NAPHTHYL)-3-(3,4,5-TRIMETHOXYPHENYL)PROP-2-EN-1-ONE
ETHYL 2-(2,6-DIBROMO-4-[3-(2-NAPHTHYL)-3-OXOPROP-1-ENYL]PHENOXY)ACETATE
4'-METHOXY-ALPHA-NAPHTHOFLAVONE
2'-METHOXY-7,8-BENZOFLAVONE
(E)-3-(2-FURYL)-1-(2-NAPHTHYL)-2-PROPEN-1-ONE
1-(2-NAPHTHYL)-3-(2-THIENYL)-2-PROPEN-1-ONE
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