ZM 306416 hydrochloride
- CAS NO.：196603-47-1
- Empirical Formula: C16H14Cl2FN3O2
- Molecular Weight: 370.21
- MDL number: MFCD08703133
- Update Date: 2023-05-18 11:31:22
What is ZM 306416 hydrochloride?
Description
ZM-306416 (196603-47-1) is a VEGF receptor tyrosine kinase inhibitor with selectivity over FGFR-1 (KDR IC50 = 100 nM; FLT IC50 = 2 μM).
The Uses of ZM 306416 hydrochloride
ZM 306416 Hydrochloride, is an inhibitor of tyrosine kinase RTK signaling pathway involved in anti-cancer agents. Anti-tumor, anti-metastatic agent.
References
1) Hennequin et al. (1999) Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors. J. Med. Chem. 42 5369
Properties of ZM 306416 hydrochloride
| storage temp. | RT |
| solubility | Soluble in DMSO (up to 5 mg/ml). |
| form | solid |
| color | White |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
Safety information for ZM 306416 hydrochloride
Computed Descriptors for ZM 306416 hydrochloride
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