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HomeProduct name listzipeprol

zipeprol

zipeprol Structural

What is zipeprol?

Originator

Respilene,Winthrop,France,1973

Definition

ChEBI: Zipeprol is a benzyl ether.

Manufacturing Process

In a reactor provided with a mechanical stirrer, a reflux refrigerant and a thermometer, there is introduced: 393 grams 1-[2-phenyl, 2-methoxy]ethyl piperazine and 22 grams 3-phenyl-3-methoxy propylene oxide in 750 ml of absolute ethanol.
When the slightly exothermic reaction (rise in temperature of about 20°C) has ceased, heating is effected for 1.5 hours at 60°C. The product is then cooled to 4°C and left to crystallize for about 12 hours. The precipitate is centrifugated then recrystallized in 500 ml of absolute ethanol.
420 grams of the desired compound is thus obtained in the form of a white, crystalline powder, melting point 83°C.

brand name

Antitaxil-z;Antituxil-z;Balutox;Broncozina;Bronx;Cerm-3024;Citizeta;Mirsol;Ogyline;Respilene;Respirase;Respirex;Santus;Talasa;Zitoxil.

Therapeutic Function

Bronchodilator

Properties of zipeprol

Melting point: 83°
Boiling point: 507.7±50.0 °C(Predicted)
Density  1.108±0.06 g/cm3(Predicted)
pka 13.97±0.20(Predicted)

Safety information for zipeprol

Computed Descriptors for zipeprol

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