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HomeProduct name list(Z)-2-decanoic acid

(Z)-2-decanoic acid

(Z)-2-decanoic acid Structural

What is (Z)-2-decanoic acid?

The Uses of (Z)-2-decanoic acid

cis-2-Decenoic Acid is an organic compound which appears to be functionally and structurally related to the class of short-chain fatty acid signaling molecules such as diffusible signal factor, which act as cell-to-cell communication molecules in bacteria and fungi.

The Uses of (Z)-2-decanoic acid

cis-2-Decenoic acid may be used to study its cytotoxic effect on the human HepG2 cell line. It has also been used to study its synergistic anti-spirochetal effect.

What are the applications of Application

cis-2-Decenoic acid is an unsaturated short chain fatty acid

Definition

ChEBI: Cis-2-decenoic acid is a 2-decenoic acid having its double bond in the cis configuration.

Biochem/physiol Actions

cis-2-Decenoic acid is a fatty acid messenger (signaling molecule) produced by Pseudomonas aeruginosa. It possesses anti-biofilm property and converts most of the cells to planktonic (free-swimming) phenotype. cis-2-Decenoic acid retains the susceptibility of the bacteria towards antimicrobial agents. It does not exhibit any toxicity towards human cells and thus, might be used for treating biofilm-associated infections. cis-2-Decenoic acid is considered active even in nano-molar ranges. It mediates the transition of dormant P. aeruginosa and Escherichia coli to their biologically active state without affecting the number of cells. cis-2-Decenoic acid is effective against E. coli and Klebsiella pneumoniae mixed-species biofilms when used along with antimicrobial agents.

Properties of (Z)-2-decanoic acid

Boiling point: 278.6±9.0 °C(Predicted)
Density  0.936
storage temp.  -20°C
solubility  DMSO : 250 mg/mL (1468.43 mM; Need ultrasonic)
form  Powder
pka 4.63±0.25(Predicted)
color  Colorless to light yellow
BRN  1721990

Safety information for (Z)-2-decanoic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.

Computed Descriptors for (Z)-2-decanoic acid

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