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HomeProduct name listYO-PRO 1

YO-PRO 1

YO-PRO 1 Structural

What is YO-PRO 1?

Definition

ChEBI: An unsymmetrical C1 cyanine dye having 1,3-benzoxazol-2-yl and quinolinium-4-yl substituents.

Biochem/physiol Actions

Oxazole yellow is a fluorescent cyanine dye that binds to DNA and is used to detect apoptotic cells. Oxazole yellow does not enter live cells. However, during apoptosis the cytoplasmic membrane becomes slightly permeable, allowing entry of the dye. Oxazole yellow is often used along with propidium iodide (catalog no. P4170), a DNA dead cell stain that does not enter either live or apoptotic cells. The λEx/λEm of Oxazole yellow is 491/509.

storage

-20°C (protect from light)

Properties of YO-PRO 1

Melting point: >250 ℃
storage temp.  2-8°C
solubility  H2O: soluble5, clear (warmed)
form  powder
color  yellow to orange-brown
λmax 491 nm
Biological Applications Nucleic acid hybridization; nucleic acid sequencing; detecting nucleic acids,cells,bacteria,immunodeficiency virus,microorganisms; counting embryoblasts,viruses; apoptosis assay; white blood cell functional assay

Safety information for YO-PRO 1

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for YO-PRO 1

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