XANTHOQUINODIN A1

CAS NO.：151063-27-3
Empirical Formula: C31H24O11
Molecular Weight: 572.52
MDL number: MFCD08457948
Update Date: 2024-10-23 13:36:13

What is XANTHOQUINODIN A1?

Biological Activity

Xanthoquinodin A1 is a fungal metabolite that has been found in Humicola and has diverse biological activities.1,2 It inhibits E. tenella schizont formation in BHK-21 cells with a minimum effective concentration (MEC) value of 0.02 μg/ml.1 Xanthoquinodin A1 is active against B. subtilis, M. luteus, S. aureus, A. laidlawii, and B. fragilis in a disc assay when used at a concentration of 1 mg/ml. It is also active against B. cereus (MIC = 0.44 μM).2 Xanthoquinodin A1 is cytotoxic to KB, MCF-7, and NCI H187 cancer cells.

References

1.Tabata, N., Suzumura, Y., Tomoda, H., et al.Xanthoquinodins, new anticoccidial agents produced by Humicola sp. Production, isolation and physico-chemical and biological propertiesJ. Antibiot. (Tokyo)46(5)749-755(1993) 2.Tantapakul, C., Promgool, T., Kanokmedhakul, K., et al.Bioactive xanthoquinodins and epipolythiodioxopiperazines from Chaetomium globosum 7s-1, an endophytic fungus isolated from Rhapis cochinchinensis (Lour.) MartNat. Prod. Res.34(4)494-502(2020)

Properties of XANTHOQUINODIN A1

Boiling point:	859.6±65.0 °C(Predicted)
Density	1.74±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
form	A solid
pka	4.50±1.00(Predicted)

Safety information for XANTHOQUINODIN A1

Computed Descriptors for XANTHOQUINODIN A1

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