XANTHOQUINODIN A1
- CAS NO.：151063-27-3
- Empirical Formula: C31H24O11
- Molecular Weight: 572.52
- MDL number: MFCD08457948
- Update Date: 2023-07-12 17:09:49
What is XANTHOQUINODIN A1?
Biological Activity
Xanthoquinodin A1 is a fungal metabolite that has been found in Humicola and has diverse biological activities.1,2 It inhibits E. tenella schizont formation in BHK-21 cells with a minimum effective concentration (MEC) value of 0.02 μg/ml.1 Xanthoquinodin A1 is active against B. subtilis, M. luteus, S. aureus, A. laidlawii, and B. fragilis in a disc assay when used at a concentration of 1 mg/ml. It is also active against B. cereus (MIC = 0.44 μM).2 Xanthoquinodin A1 is cytotoxic to KB, MCF-7, and NCI H187 cancer cells.
References
1.Tabata, N., Suzumura, Y., Tomoda, H., et al.Xanthoquinodins, new anticoccidial agents produced by Humicola sp. Production, isolation and physico-chemical and biological propertiesJ. Antibiot. (Tokyo)46(5)749-755(1993) 2.Tantapakul, C., Promgool, T., Kanokmedhakul, K., et al.Bioactive xanthoquinodins and epipolythiodioxopiperazines from Chaetomium globosum 7s-1, an endophytic fungus isolated from Rhapis cochinchinensis (Lour.) MartNat. Prod. Res.34(4)494-502(2020)
Properties of XANTHOQUINODIN A1
| Boiling point: | 859.6±65.0 °C(Predicted) |
| Density | 1.74±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
| form | A solid |
| pka | 4.50±1.00(Predicted) |
Safety information for XANTHOQUINODIN A1
Computed Descriptors for XANTHOQUINODIN A1
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