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HomeProduct name listVENTURICIDIN A

VENTURICIDIN A

  • CAS NO.:33538-71-5
  • Empirical Formula: C41H67NO11
  • Molecular Weight: 749.97
  • MDL number: MFCD00036323
  • EINECS: 251-568-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-23 13:36:13
VENTURICIDIN A Structural

What is VENTURICIDIN A?

Description

Venturicidin A is a macrolide antibiotic isolated from strains of Streptomyces. It is active against fungi in the genus Venturia which cause apple scab, as well as other fungi, but not against higher plants. Venturicidin A is also cytotoxic against trypanosomes (IC50 = 120-540 ng/ml) while being more than 25,000 times less effective against mammalian cells. It inhibits bacterial and mitochondrial ATP synthases.

The Uses of VENTURICIDIN A

The macrolide antibiotic, Venturicidin A, isolated from a Streptomyces sp., is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. Venturicidin A was originally isolated as an antifungal agent.

The Uses of VENTURICIDIN A

Venturicidin A is an antibiotic and potent inhibitor of mitochondrial ATP synthase.

What are the applications of Application

Venturicidin A is an antibiotic and potent inhibitor of mitochondrial ATP synthase

Definition

ChEBI: Venturicidin a is a diterpene lactone.

Properties of VENTURICIDIN A

Melting point: 145-147°; mp 140-142°
Boiling point: 874.9±65.0 °C(Predicted)
alpha  D +119° (c = 0.5 in chloroform)
Density  1.16±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
pka 11.80±0.70(Predicted)
form  White to off-white solid.

Safety information for VENTURICIDIN A

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for VENTURICIDIN A

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