VAR10300 dihydrochloride
Synonym(s):5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline dihydrochloride;M-30 dihydrochloride;VAR10300 dihydrochloride
- CAS NO.：64821-19-8
- Empirical Formula: C14H15ClN2O
- Molecular Weight: 262.74
- MDL number: MFCD20488063
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-07 19:09:50
What is VAR10300 dihydrochloride?
The Uses of VAR10300 dihydrochloride
M 30 Dihydrochloride is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA (Cat. No. 2547) induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson''s disease model.
Storage
Store at -20°C
Properties of VAR10300 dihydrochloride
| storage temp. | 2-8°C |
| solubility | DMSO, heptane and xylene: ≥21mg/mL |
| form | powder |
| color | green-yellow |
| Water Solubility | Soluble to 100 mM in water |
Safety information for VAR10300 dihydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for VAR10300 dihydrochloride
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