vanoxonin
- CAS NO.：86933-99-5
- Empirical Formula: C18H25N3O9
- Molecular Weight: 427.408
- MDL number: MFCD01939818
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-21 10:59:17
What is vanoxonin?
Biological Activity
Vanoxonin is a bacterial metabolite that has been found in S. hirsuta.1 It forms a complex with vanadium, and the complex inhibits thymidylate synthetase with an IC50 value of 0.7 μg/ml. The vanoxonin-vanadium complex is cytotoxic to L1210 leukemia cells (MIC = 25 μg/ml) and increases survival in Ehrlich murine spontaneous adenocarcinoma and L1210 mouse tumor models.
References
1.Kanai, F., Sawa, T., Hamada, M., et al.Vanoxonin, a new inhibitor of thymidylate synthetaseJ. Antibiot. (Tokyo)36(6)656-660(1983)
Properties of vanoxonin
| storage temp. | -20°C |
| form | A solid |
Safety information for vanoxonin
Computed Descriptors for vanoxonin
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