UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT
Synonym(s):UDP-α-D-N-Acetylglucosamine, Disodium Salt - CAS 91183-98-1 - Calbiochem;UDPAG;UDP-GlcNAc;UDP-GlcNAc, 2Na;UDP-N-acetylglucosamine
- CAS NO.：91183-98-1
- Empirical Formula: C17H28N3NaO17P2
- Molecular Weight: 631.35
- MDL number: MFCD00799985
- EINECS: 293-820-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:10
What is UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT?
Chemical properties
White to off-white crystalline powder
The Uses of UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT
Uridine-5'-diphospho-N-acetylglucosamine sodium salt is used as a chemical reagent in studies relating to the synthesis of immunogens.
The Uses of UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT
GlcNAc transferase substrate
The Uses of UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT
Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) sodium salt has been used:
- as a component of reaction cocktail in endoplasmic reticulum to Golgi transport assay
- as a reference standard for the quantification of UDP-GlcNAc in liver tissues using high-performance liquid chromatography (HPLC)
- in testing the glycosylation activity of O-GlcNAc transferase (OGT) against peptide substrate
What are the applications of Application
UDP-N-acetyl-D-glucosamine disodium salt is a nucleotide sugar and donor substrate for O-GlcNAc transferase.
General Description
Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a nucleotide sugar. It is synthesized from glucose via the hexosamine biosynthetic pathway (HBP). UDP-GlcNAc is transported actively into Golgi, nucleotide sugar transporter (NST). The levels of UDP-GlcNAc is modulated by the concentration of nutrients exposed to the cell.
Biochem/physiol Actions
Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a sugar donor and aids in the endomembrane glycosylation of endoplasmic reticulum and Golgi. The decreased levels of UDP-GlcNAc has an influence on the normal cellular proliferation and apoptosis. UDP-GlcNAc elicits feedback inhibition of the enzyme glutamine:fructose-6-phosphate amidotransferase (GFAT).
Properties of UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT
| storage temp. | -20°C |
| solubility | Methanol (Slightly, Heated), Water (Slightly) |
| form | Solid |
| color | White to off-White |
Safety information for UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT
Computed Descriptors for UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT
New Products
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