TRIS(2-DIMETHYLAMINOETHYL)AMINE

Synonym(s):Me₆TREN

CAS NO.：33527-91-2
Empirical Formula: C12H30N4
Molecular Weight: 230.39
MDL number: MFCD00015607
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

TRIS(2-DIMETHYLAMINOETHYL)AMINE Structural

What is TRIS(2-DIMETHYLAMINOETHYL)AMINE?

Chemical properties

Clear colorless to yellow liquid

The Uses of TRIS(2-DIMETHYLAMINOETHYL)AMINE

Tris(2-dimethylaminoethyl)amine is used as an atom transfer radical polymerization (ATRP) ligand for the creation of telechelic polymers. It is a tripodal polyamine ligand and forms complexes with group 1 metals, which is used in alkali-metal-mediated synthetic applications. Further, it is involved in the macrocyclization processes by reacting with tripodal esters in methanol to give tricyclic cryptands.

General Description

Tris[2-(dimethylamino)ethyl]amine (Me₆TREN) is an aliphatic tertiary amine that forms a quadridentate ligand. It is majorly used in atom transfer radical polymerization (ATRP). It is a hexamethyl derivative of (2-aminoethyl)amine, also known as trenMe. It can be prepared by a modification of Ristempart′s synthesis.

Properties of TRIS(2-DIMETHYLAMINOETHYL)AMINE

Boiling point:	88℃ (1.9 Torr)
Density	0.862 g/mL at 25 °C
Flash point:	104℃
refractive index	1.4540
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	8.99±0.50(Predicted)
form	clear liquid
color	Colorless to Light orange to Yellow
Water Solubility	Miscible with water.
Sensitive	Air Sensitive & Hygroscopic
EPA Substance Registry System	1,2-Ethanediamine, N1,N1-bis[2-(dimethylamino)ethyl]-N2,N2-dimethyl- (33527-91-2)

Safety information for TRIS(2-DIMETHYLAMINOETHYL)AMINE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.