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HomeProduct name listtrans-Tranilast

trans-Tranilast

trans-Tranilast Structural

What is trans-Tranilast?

The Uses of trans-Tranilast

trans-Tranilast is used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.

The Uses of trans-Tranilast

Antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.

Definition

ChEBI: Tranilast is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 3,4-dimethoxycinnamoyl group. It has a role as an anti-asthmatic drug, a nephroprotective agent, an anti-allergic agent, a calcium channel blocker, an antineoplastic agent, an aryl hydrocarbon receptor agonist and a hepatoprotective agent. It is a member of cinnamamides, a dimethoxybenzene, an amidobenzoic acid and a secondary carboxamide. It is functionally related to an anthranilic acid.

Properties of trans-Tranilast

Melting point: 184 °C(Solv: water (7732-18-5); acetone (67-64-1))
Boiling point: 585.6±50.0 °C(Predicted)
Density  1.299±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO: 100 mg/mL (305.50 mM)
pka 3.45±0.36(Predicted)
form  Solid
color  White to off-white

Safety information for trans-Tranilast

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for trans-Tranilast

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