trans-Tranilast

CAS NO.：70806-55-2
Empirical Formula: C18H17NO5
Molecular Weight: 327.33
MDL number: MFCD00864787
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-09 19:38:33

What is trans-Tranilast?

The Uses of trans-Tranilast

trans-Tranilast is used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.

The Uses of trans-Tranilast

Antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.

Definition

ChEBI: Tranilast is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 3,4-dimethoxycinnamoyl group. It has a role as an anti-asthmatic drug, a nephroprotective agent, an anti-allergic agent, a calcium channel blocker, an antineoplastic agent, an aryl hydrocarbon receptor agonist and a hepatoprotective agent. It is a member of cinnamamides, a dimethoxybenzene, an amidobenzoic acid and a secondary carboxamide. It is functionally related to an anthranilic acid.

Properties of trans-Tranilast

Melting point:	184 °C(Solv: water (7732-18-5); acetone (67-64-1))
Boiling point:	585.6±50.0 °C(Predicted)
Density	1.299±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO: 100 mg/mL (305.50 mM)
pka	3.45±0.36(Predicted)
form	Solid
color	White to off-white

Safety information for trans-Tranilast

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.