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HomeProduct name listTrans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid

Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid

Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid Structural

What is Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid?

Description

Trans-4-(Maleimidomethyl) cyclohexanecarboxylic Acid is a kind of carboxylate, being well known for its N-hydroxysuccinimide ester derivative (SMCC), which is a useful cross-linking reagent. SMCC is widely used for the generation of stable maleimide-activated carrier proteins, enzyme immunoconjugates and hapten carrier molecule conjugates. It can be used for the coupling of a peptide to an amino group.

References

https://www.aatbio.com/products/smcc-4-n-maleimidomethyl-cyclohexanecarboxylic-acid-n-hydroxysuccinimide-ester-cas-64987-85-5
http://www.sigmaaldrich.com/catalog/product/sigma/m5525?lang=en&region=US
Zhang, Hongyan, et al. "Antifreeze protein detection using Rhodamine B as photoluminescence label inporous silicon." Current Applied Physics13.4(2013):736-742.

Properties of Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid

Melting point: 144 °C(Solv: benzene (71-43-2))
Boiling point: 433.6±18.0 °C(Predicted)
Density  1.329
storage temp.  Sealed in dry,Room Temperature
solubility  soluble in Methanol
pka 4.80±0.10(Predicted)
form  powder to crystal
color  White to Almost white
CAS DataBase Reference 69907-67-1

Safety information for Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid

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