Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester
- CAS NO.:168958-19-8
- Empirical Formula: C12H19NO4
- Molecular Weight: 241.28
- MDL number: MFCD30729673
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-25 17:59:01
What is Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester?
The Uses of Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester
(1R,4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Properties of Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester
Boiling point: | 331.2±42.0 °C(Predicted) |
Density | 1.10±0.1 g/cm3(Predicted) |
solubility | soluble in Methanol |
pka | 11.75±0.40(Predicted) |
Safety information for Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester
Computed Descriptors for Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Ivermectin EP Impurity B Rimegepant Impurity 3 Tubulysin E Tubulysin G (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin M Potassium HMDS (1.0 M in THF) Fuel shell Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Methyl 4-amino-3-(4-phenylpiperazin-1-yl)benzoate 3,3,6,6-Tetramethylcyclohexane-1,2-dione 2-(3,5-Di-tert-butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 5-Aminophthalazine 4-Bromo-N,N-bis(4-iodophenyl)aniline 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 1,3,5-Trimethyl-1,4-cyclohexadiene Boronic acid, [4-(2-aminoethyl)phenyl]Related products of tetrahydrofuran
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