Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester

CAS NO.：168958-19-8
Empirical Formula: C12H19NO4
Molecular Weight: 241.28
MDL number: MFCD30729673
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-25 17:59:01

What is Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester?

The Uses of Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester

(1R,4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Properties of Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester

Boiling point:	331.2±42.0 °C(Predicted)
Density	1.10±0.1 g/cm3(Predicted)
solubility	soluble in Methanol
pka	11.75±0.40(Predicted)

Safety information for Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester

Computed Descriptors for Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester

New Products

4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acid

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