Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listTrans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine Structural

What is Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine?

Description

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine is a useful research chemical for organic synthesis and other chemical processes.

The Uses of Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine

trans-N,N′-dimethylcyclohexane-1,2-diamine can be used as a ligand in the synthesis of the following products via copper catalyzed C-N coupling reactions:

  • vinylsulfoximines obtained from NH sulfoximes and vinyl bromides
  • N-arylpyridones obtained via reaction between 2-substituted pyridines and aryl halides
  • N-aryl amines obtained via reaction between amines and aryl iodides/aryl bromides

Synthesis

Cyclohexene oxide (1) was reacted with 25–30% aqueous methylamine (1.5 equiv.) in a sealed reactor to form trans-2-(methylamino)cyclohexanol 2 at 80 °C within 5h. Compound 2 was subjected to Mitsunobu reaction at room temperature, followed by adjusting the pH from 2 to 10 to yield 7-methyl-7-azabicyclo[4.1.0]-heptane 3, which was directly subjected to the following reaction without purification. Ring-opening reactions of compound 3 with a methylamine aqueous solution were completed in a sealed reactor at 110 °C after 6h to yield Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine.
Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine

Properties of Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine

Melting point: 4°C
Boiling point: 83 °C / 13mmHg
Density  0.89
refractive index  n20/D1.472(lit.)
Flash point: 60℃
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
form  liquid
pka 11.04±0.40(Predicted)
color  colorless to pale yellow
Sensitive  air sensitive
InChI InChI=1/C8H18N2/c1-9-7-5-3-4-6-8(7)10-2/h7-10H,3-6H2,1-2H3/t7-,8-/s3
CAS DataBase Reference 67579-81-1(CAS DataBase Reference)

Safety information for Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H314:Skin corrosion/irritation
Precautionary Statement Codes P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine

InChIKey JRHPOFJADXHYBR-HTQZYQBOSA-N
SMILES [C@@H]1(NC)CCCC[C@H]1NC |&1:0,7,r|

Related products of tetrahydrofuran

You may like

  • trans-N,N'-Dimethylcyclohexane-1,2-diamine 96% CAS 67579-81-1
    trans-N,N'-Dimethylcyclohexane-1,2-diamine 96% CAS 67579-81-1
    67579-81-1
    View Details
  • trans-N,N′-Dimethylcyclohexane-1,2-diamine, 97% CAS 67579-81-1
    trans-N,N′-Dimethylcyclohexane-1,2-diamine, 97% CAS 67579-81-1
    67579-81-1
    View Details
  • trans-N,N'-Dimethylcyclohexane-1,2-diamine CAS 67579-81-1
    trans-N,N'-Dimethylcyclohexane-1,2-diamine CAS 67579-81-1
    67579-81-1
    View Details
  • trans-N,N′-Dimethylcyclohexane-1,2-diamine CAS 67579-81-1
    trans-N,N′-Dimethylcyclohexane-1,2-diamine CAS 67579-81-1
    67579-81-1
    View Details
  • 1823368-42-8 98%
    1823368-42-8 98%
    1823368-42-8
    View Details
  • 2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    1307449-08-6
    View Details
  • Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    25408-95-1
    View Details
  • Lithium Clavulanate
    Lithium Clavulanate
    61177-44-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.