Tos-PEG5-CH2CO2t-butyl ester
- CAS NO.：169751-73-9
- Empirical Formula: C21H34O9S
- Molecular Weight: 462.55
- MDL number: MFCD27977499
- Update Date: 2024-10-28 16:48:35
What is Tos-PEG5-CH2CO2t-butyl ester?
Description
Tos-PEG5-CH2CO2tBu is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
Properties of Tos-PEG5-CH2CO2t-butyl ester
| Boiling point: | 550.0±50.0 °C(Predicted) |
| Density | 1.163±0.06 g/cm3(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for Tos-PEG5-CH2CO2t-butyl ester
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Tos-PEG5-CH2CO2t-butyl ester
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