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HomeProduct name listTigecycline Hydrochloride

Tigecycline Hydrochloride

Tigecycline Hydrochloride Structural

What is Tigecycline Hydrochloride?

Biological Activity

Tigecycline hydrochloride (GAR-936 hydrochloride) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline against E. coli (strain MG1655) is approximately 125 ng/mL. The MIC50 and MIC90 for Acinetobacter baumannii (A. baumannii) were 1 and 2 mg/L, respectively.

in vitro

Tigecycline (0.63-30 μM, preincubated for 4 days, treated for 72 h) inhibits AML2 cells and HL-60 cells with IC 50 s of 4.72±0.54 and 3.06±0.85 μM (freshly prepared).

in vivo

Tigecycline (50 mg/kg; intraperitoneal injection; twice a day; for 11 days) reduces tumor volume and weight in NOD/SCID mice.

Properties of Tigecycline Hydrochloride

storage temp.  Store at -20°C
solubility  Soluble in DMSO
form  Powder

Safety information for Tigecycline Hydrochloride

Computed Descriptors for Tigecycline Hydrochloride

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