thiocolchicine
Synonym(s):10-Demethoxy-10-(methylthio)colchicine;10-Thio-colchicine;N-[(7S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-acetamide;NSC 186301
- CAS NO.:2730-71-4
- Empirical Formula: C22H25NO5S
- Molecular Weight: 415.5
- MDL number: MFCD01736965
- EINECS: 220-346-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:02:20
What is thiocolchicine?
Chemical properties
Bright Yellow Solid
The Uses of thiocolchicine
A muscle relaxant.
What are the applications of Application
Thiocolchicine is a specific tubulin synthesis inhibitor and Topo I inhibitor
Biochem/physiol Actions
Thiocolchicine is an antimitotic alkaloid and apoptosis inducer that inhibits tubulin polymerization and microtubule assembly.
Properties of thiocolchicine
Melting point: | 193℃ |
Boiling point: | 729.1±60.0 °C(Predicted) |
alpha | D20 -221° |
Density | 1.27±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMSO: soluble10mg/mL, clear |
pka | 14.75±0.40(Predicted) |
form | powder |
color | white to beige |
Safety information for thiocolchicine
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 |
GHS Hazard Statements |
H318:Serious eye damage/eye irritation H340:Germ cell mutagenicity |
Precautionary Statement Codes |
P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for thiocolchicine
Abamectin manufacturer
Supriya Lifescience Ltd
1Y
Phone:+919820804279
Whatsapp: +91 9821266261
product: 2730-71-4 Thiocolchicine 99%
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