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HomeProduct name listtert-Butyl 2-bromo-4-fluorobenzoate

tert-Butyl 2-bromo-4-fluorobenzoate

tert-Butyl 2-bromo-4-fluorobenzoate Structural

What is tert-Butyl 2-bromo-4-fluorobenzoate?

The Uses of tert-Butyl 2-bromo-4-fluorobenzoate

tert-Butyl 4-Bromo-2-fluorobenzoate is an intermediate of enzalutamide (M199800). Enzalutamide is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.

Properties of tert-Butyl 2-bromo-4-fluorobenzoate

Boiling point: 305.7±27.0 °C(Predicted)
Density  1.394±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Oil
color  Clear Colourless

Safety information for tert-Butyl 2-bromo-4-fluorobenzoate

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H227:Flammable liquids
H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for tert-Butyl 2-bromo-4-fluorobenzoate

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