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HomeProduct name listtert-Butyl 2-(aminomethyl)phenylcarbamate

tert-Butyl 2-(aminomethyl)phenylcarbamate

Synonym(s):(2-Aminomethyl-phenyl)-carbamic acid tert-butyl ester;tert-Butyl N-(2-aminomethylphenyl)carbamate

tert-Butyl 2-(aminomethyl)phenylcarbamate Structural

What is tert-Butyl 2-(aminomethyl)phenylcarbamate?

The Uses of tert-Butyl 2-(aminomethyl)phenylcarbamate

Tert-Butyl 2-(aminomethyl)phenylcarbamate can be used as reactant for Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines employing a double UDC (Ugi/Deprotect/Cyclize)

The Uses of tert-Butyl 2-(aminomethyl)phenylcarbamate

Reactant for:

  • Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines employing a double UDC (Ugi/Deprotect/Cyclize) strategy
  • Preparation of hydroquinazoline scaffolds via microwave-promoted Ugi reaction and cyclization
  • Preparation of pyrazinone inhibitors of mast cell tryptase

Properties of tert-Butyl 2-(aminomethyl)phenylcarbamate

Boiling point: 238-242℃
Density  1.054g/mLat 25℃
Flash point: 71°C
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
pka 13.67±0.70(Predicted)

Safety information for tert-Butyl 2-(aminomethyl)phenylcarbamate

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H317:Sensitisation, Skin
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.

Computed Descriptors for tert-Butyl 2-(aminomethyl)phenylcarbamate

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