Tamsulosin hydrochloride
Synonym(s):5-[2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride
- CAS NO.：80223-99-0
- Empirical Formula: C20H29ClN2O5S
- Molecular Weight: 444.97
- MDL number: MFCD09954593
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-18 17:01:59
What is Tamsulosin hydrochloride?
Chemical properties
White to Off-White Solid
The Uses of Tamsulosin hydrochloride
Tamsulosin hydrochloride is a specific ;1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy.
The Uses of Tamsulosin hydrochloride
Tamsulosin is a specific α1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy.
Clinical Use
Treatment of benign prostatic hyperplasia
Drug interactions
Potentially hazardous interactions with other drugs
Anaesthetics: enhanced hypotensive effect.
Antidepressants: enhanced hypotensive effect with
MAOIs.
Antifungals: concentration increased by
ketoconazole.
Avanafil, vardenafil, sildenafil and tadalafil: enhanced
hypotensive effect, avoid concomitant use.
Beta-blockers: enhanced hypotensive effect;
increased risk of first dose hypotensive effect.
Calcium-channel blockers: enhanced hypotensive
effect; increased risk of first dose hypotensive effect.
Diuretics: enhanced hypotensive effect; increased
risk of first dose hypotensive effect.
Moxisylyte: possibly severe postural hypotension.
Metabolism
Tamsulosin is metabolised slowly in the liver primarily by the cytochrome P450 isoenzymes CYP2D6 and CYP3A4; it is excreted mainly in the urine as metabolites and some unchanged drug
Properties of Tamsulosin hydrochloride
| Melting point: | 254-256 °C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | neat |
Safety information for Tamsulosin hydrochloride
Computed Descriptors for Tamsulosin hydrochloride
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]aMino]propyl]-2-Methoxybenzenesulfonic Acid](https://img.chemicalbook.in/CAS/GIF/890708-67-5.gif)
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