TAFENOQUINE SUCCINATE
Synonym(s):N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine;SB-252263;WR 238605
- CAS NO.：106635-81-8
- Empirical Formula: C28H34F3N3O7
- Molecular Weight: 581.5806696
- MDL number: MFCD00892249
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-20 16:43:00
What is TAFENOQUINE SUCCINATE?
The Uses of TAFENOQUINE SUCCINATE
Tafenoquine succinate is a new 8-aminoquinoline with an improved therapeutic index and safety profile as compared to primaquine (P733500).Tafenoquine has the potential to become a widely used drug in the preven tion and treatment of malaria infection and could replace some currently used drugs as resistant strains of Plasmodium species increase.
The Uses of TAFENOQUINE SUCCINATE
Tatenoquine is a new 8-aminoquinoline with an improved therapeutic index and safety profile as compared to primaquine (P733500).Tafenoquine has the potential to become a widely used drug in the prevention and treatment of malaria infection and could replace some currently used drugs as resistant strains of Plasmodium species increase.
Biochem/physiol Actions
Tafenoquine is an antimalarial primaquine analog being investigated to treat and prevent Plasmodium vivax infections. It can eliminate both blood and liver stages of Plasmodium vivax. Tafenoquine has also been tested as a therapy for leishmaniasis.
Properties of TAFENOQUINE SUCCINATE
| Melting point: | 146-149° |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble5mg/mL (clear solution) |
| form | powder |
| color | white to beige |
Safety information for TAFENOQUINE SUCCINATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for TAFENOQUINE SUCCINATE
TAFENOQUINE SUCCINATE manufacturer
Humble Healthcare Limited
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