t-Boc-N-amido-PEG2-acid
- CAS NO.：1365655-91-9
- Empirical Formula: C12H23NO6
- Molecular Weight: 277.31
- MDL number: MFCD22056304
- Update Date: 2024-10-28 23:16:16
What is t-Boc-N-amido-PEG2-acid?
Description
t-Boc-N-amido-PEG2-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Properties of t-Boc-N-amido-PEG2-acid
| Boiling point: | 429.9±35.0 °C(Predicted) |
| Density | 1.125±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 4.28±0.10(Predicted) |
| color | Colorless to light yellow |
Safety information for t-Boc-N-amido-PEG2-acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for t-Boc-N-amido-PEG2-acid
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