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HomeProduct name listSitagliptin Impurity 10

Sitagliptin Impurity 10

Sitagliptin Impurity 10 Structural

What is Sitagliptin Impurity 10?

The Uses of Sitagliptin Impurity 10

1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985), which is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Properties of Sitagliptin Impurity 10

Boiling point: 542.2±60.0 °C(Predicted)
Density  1.61±0.1 g/cm3(Predicted)
solubility  Chloroform (Slightly), Methanol (Slightly)
pka 13.69±0.20(Predicted)
form  Solid
color  White to Off-White

Safety information for Sitagliptin Impurity 10

Computed Descriptors for Sitagliptin Impurity 10

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