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HomeProduct name listSennoside B

Sennoside B

  • CAS NO.:128-57-4
  • Empirical Formula: C42H38O20
  • Molecular Weight: 862.74
  • MDL number: MFCD00151528
  • EINECS: 204-895-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-05 19:05:58
Sennoside B Structural

What is Sennoside B?

Chemical properties

White to brown powder

The Uses of Sennoside B

Sennoside B is used in the inhibition of platelet driven growth factor (PDGF) used and may inhibit proliferative disease which depend upon the PDGF pathway. Laxative.

What are the applications of Application

Sennoside B is a PDGF inihibitor

Definition

ChEBI: A member of the class of sennosides that is (9R,9'S)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4', by beta-D glucopyranosyloxy groups at positions 5 and 5', and by oxo groups at positions 10 and 10'.

Purification Methods

Sennoside B forms yellow crystals from aqueous acetone or large volumes of H2O. [Stoll et al. Helv Chim Acta 32 1896 1900, Beilstein 17 III/IV 3402.]

Properties of Sennoside B

Melting point: 209~212℃
Boiling point: 698.48°C (rough estimate)
alpha  D20 -100° (c = 0.2 in 70% acetone); D20 -67° (c = 0.4 in 70% dioxane)
Density  1.3066 (rough estimate)
refractive index  1.7630 (estimate)
storage temp.  2-8°C
solubility  DMSO (Very Slightly, Heated), Methanol (Slightly, Heated)
form  neat
pka 3.31±0.40(Predicted)
form  Solid
color  Light Yellow to Dark Yellow
BRN  5723747
Stability: Hygroscopic
CAS DataBase Reference 128-57-4(CAS DataBase Reference)

Safety information for Sennoside B

Computed Descriptors for Sennoside B

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