SELEXIPAG interMediate
- CAS NO.:475086-75-0
- Empirical Formula: C23H27N3O
- Molecular Weight: 361.48
- MDL number: MFCD28411750
- EINECS: 813-799-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-22 21:24:34
What is SELEXIPAG interMediate?
The Uses of SELEXIPAG interMediate
4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.
What are the applications of Application
Selexipag interMediate is a synthetic organic compound that is used as an intermediate in the synthesis of oxychloride. It is an oxychloride with a nucleophilic substitution reaction. The reaction proceeds selectively at the phosphorus atom and gives high yield. The reactivity of 4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butan-1-ol is enhanced by the use of n butanol, which also acts as a solvent for the reaction. The product can be purified by filtration or recrystallization from hexane with piperazine as a reagent.
Properties of SELEXIPAG interMediate
Melting point: | 68 - 71°C |
Boiling point: | 514.4±50.0 °C(Predicted) |
Density | 1.112±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), DMSO (Slightly) |
form | Solid |
pka | 15.05±0.10(Predicted) |
color | Pale Yellow to Light Yellow |
Safety information for SELEXIPAG interMediate
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for SELEXIPAG interMediate
Abamectin manufacturer
Lakshmi Farmachem
Aventus Labs
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