Secretin
- CAS NO.：17034-35-4
- Empirical Formula: C130H220N44O41
- Molecular Weight: 3055.41
- MDL number: MFCD00133810
- EINECS: 241-105-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:54:57
What is Secretin?
Description
Secretin was the first hormone identified. It is a secretagogue of pancreatic digestive juices from the porcine duodenum, used to aid in the diagnosis of gastrinoma. Secretin was discovered by Bayliss and Starling in 1902 as a secretagogue of pancreatic juices from the porcine duodenum. It was the first hormone identified.
The Uses of Secretin
Stimulates pancreatic and gastric secretions to aid in the diagnosis of pancreatic exocrine dysfunction and the diagnosis of gastrinoma.
brand name
SecretinKabi (KabiVitrum, Sweden).
General Description
Secretin is a 27-amino-acid polypeptide that is structurallysimilar to glucagon. The presence of acid in the small intestineis the most important physiological stimulus for the secretionof secretin. The primary action of secretin is on pancreatic acinarcells that regulate the secretion of water and bicarbonate.Secretin also promotes the secretion of pancreatic enzymes, toa lesser extent. Secretin inhibits the release of gastrin and,therefore, gastric acid. It also increases stomach-emptyingtime by reducing the contraction of the pyloric sphincter.
Clinical Use
Recombinant human secretin (SecreFlo, ChiRhoStim) is approved for use in stimulating gastrin secretion to aid in the diagnosis of gastrinoma.
Properties of Secretin
| Density | 1.50±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble |
| form | powder |
| color | White to off-white |
| CAS DataBase Reference | 17034-35-4 |
Safety information for Secretin
Computed Descriptors for Secretin
New Products
3-N-BOC-(S)-AMINO BUTYRONITRILE 4,4-DIFLUOROCYCLOHEXANAMINE 1-Boc-5-broMo-1H-pyrazolo[3,4-b]pyridine 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 3-FLUOROPYRROLIDINE HYDROCHLORIDE 4-Methylenepiperidine HCl 5-(((S)-2-amino-3-(4-carbamoyl-2,6-dimethylphenyl)-N-((S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl)propanamido)methyl)-2-methoxybenzoic acid 1,1,1-trimethyl-N-((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)-N-(trimethylsilyl)silanamine (S)-2-((tert-butoxycarbonyl)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid methyl (S)-2-methoxy-5-(((1-(4-phenyl-1H-imidazol-2-yl)ethyl)amino)methyl)benzoate Dimethyl Bicyclo[2.2.1]Hepta-2,5-Diene-2,3-Dicarboxylate methyl 4-acetamido-5-chloro-2-hydroxybenzoate 7-Methoxyquinoline-4-carbonitrile 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acid SIDCHEM MB-05 Sidchem BT 20 Sidchem 730 SIDCHEM BN 750 Sidchem BT 10 Sidchem 715 RIFAXIMIN EP IMPURITY 2 PIMECROLIMUS TAUTOMER II CLINDAMYCIN 2,3-PALMITATERelated products of tetrahydrofuran
You may like
-
5006-66-6 98%View Details
5006-66-6 -
4-Hydroxy-7-methoxyquinoline 98%View Details
82121-05-9 -
(E)-4-(3,5-Dimethoxystyryl)phenol 537-42-8 98%View Details
537-42-8 -
136-77-6 4-Hexylbenzene-1,3-diol 98%View Details
136-77-6 -
816449-02-2 98%View Details
816449-02-2 -
1H-Imidazole-4-carbonitrile 98%View Details
57090-88-7 -
18979-61-8 4-Butylbenzene-1,3-diol, 98%View Details
18979-61-8 -
861620-90-8 98%View Details
861620-90-8