(S)-N-Fmoc-2-(2'-propylenyl)alanine
Synonym(s):(S)-N-Fmoc-α-2-n-propenylalanine;Fmoc-(S)-2-(2-propenyl)alanine;Fmoc-(S)-2-amino-2-methyl-4-pentenoic acid
- CAS NO.：288617-71-0
- Empirical Formula: C21H21NO4
- Molecular Weight: 351.4
- MDL number: MFCD02682444
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is (S)-N-Fmoc-2-(2'-propylenyl)alanine?
The Uses of (S)-N-Fmoc-2-(2'-propylenyl)alanine
Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.
Properties of (S)-N-Fmoc-2-(2'-propylenyl)alanine
| Boiling point: | 564.3±45.0 °C(Predicted) |
| Density | 1.224 |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| form | liquid |
| pka | 3.81±0.11(Predicted) |
| color | pale yellow |
Safety information for (S)-N-Fmoc-2-(2'-propylenyl)alanine
| Signal word | Warning |
| Pictogram(s) |
 Environment GHS09 |
| GHS Hazard Statements |
H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. |
Computed Descriptors for (S)-N-Fmoc-2-(2'-propylenyl)alanine
| InChIKey | FNCSRFHDUZYOCR-NRFANRHFSA-N |
New Products
Tubulysin E Tubulysin G (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate 2,2-diethoxyethanethioamide 4-(Benzyloxy)-3-bromophenylacetic Acid 4,4-DIFLUOROPIPERIDINE 1-(1,1-Difluoroethyl)-2-fluorobenzene 4,4-DIFLUOROCYCLOHEXANAMINE Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) Imeglimin Hydrochloride IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Fuel shell 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Magnesium Trisilicate Lubiprostone Latanoprostene Bunod Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
You may like
-
(R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonateView Details
2416850-45-6 -
methyl 3-fluoro-4- thiomorpholino phenylcarbamateView Details
2760359-22-4 -
Fuel shell 98%View Details -
4,6-dichloro-2-propylthiopyrimidine-5-amine 145783-15-9 98%View Details
145783-15-9 -
Hydrogen Gas 98%View Details
-
151767-02-1 Montelukast Sodium IP/USP 98%View Details
151767-02-1 -
Valacyclovir Hydrochloride IH 98%View Details
124832-27-5 -
2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 98%View Details
142569-70-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.