S-acetyl-PEG6-alcohol
- CAS NO.：1352221-63-6
- Empirical Formula: C14H28O7S
- Molecular Weight: 340.43
- MDL number: MFCD22574786
- Update Date: 2024-03-25 07:34:14
What is S-acetyl-PEG6-alcohol?
Biological Activity
S-acetyl-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of S-acetyl-PEG6-alcohol
| Boiling point: | 441.7±45.0 °C(Predicted) |
| Density | 1.134±0.06 g/cm3(Predicted) |
| pka | 14.36±0.10(Predicted) |
Safety information for S-acetyl-PEG6-alcohol
Computed Descriptors for S-acetyl-PEG6-alcohol
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