(S)-4-Hydroxy-2-pyrrolidinone
Synonym(s):(S)-β-Hydroxy-γ-butyrolactam
- CAS NO.：68108-18-9
- Empirical Formula: C4H7NO2
- Molecular Weight: 101.1
- MDL number: MFCD00273370
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-08 14:48:35
What is (S)-4-Hydroxy-2-pyrrolidinone?
Chemical properties
White crystal
The Uses of (S)-4-Hydroxy-2-pyrrolidinone
The (S)-enantiomer intermediate in the preparation of Oxiracetam
The Uses of (S)-4-Hydroxy-2-pyrrolidinone
(S)-(?)-4-Hydroxy-2-pyrrolidinone can be used as a starting material in the preparation of:
- Biologically significant pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives.
- Substituted azepanes by reacting with various aldehydes via photochemical [5+2] cycloaddition.
General Description
4-Hydroxy-2-pyrrolidinone is an important building block found in many bioactive compounds like streptopyrrolidine. It can be used as an intermediate in the synthesis of various γ-amino acids (GABA) and substituted 2-pyrrolidinones like cynometrine and cynodine.
Properties of (S)-4-Hydroxy-2-pyrrolidinone
| Melting point: | 156-159 °C (lit.) |
| Boiling point: | 363.6±35.0 °C(Predicted) |
| alpha | -41 º (c=% in ethanol) |
| Density | 1.292±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| Water Solubility | Slightly soluble in water |
| form | Solid |
| pka | 13.62±0.20(Predicted) |
| color | White to off-white |
| optical activity | [α]23/D 43°, c = 1 in ethanol |
| BRN | 1524192 |
| CAS DataBase Reference | 68108-18-9(CAS DataBase Reference) |
Safety information for (S)-4-Hydroxy-2-pyrrolidinone
| Signal word | Warning |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (S)-4-Hydroxy-2-pyrrolidinone
| InChIKey | IOGISYQVOGVIEU-VKHMYHEASA-N |
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![2-[(carbamoylmethyl)amino]acetamide](https://img.chemicalbook.in/CAS/GIF/21954-96-1.gif)
You may like
-
68108-18-9 (S)-4-Hydroxy-2-pyrrolidinone 98%View Details
68108-18-9 -
(S)-(-)-4-Hydroxy-2-pyrrolidone CAS 68108-18-9View Details
68108-18-9 -
(S)-(−)-4-Hydroxy-2-pyrrolidinone CAS 68108-18-9View Details
68108-18-9 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.