(S)-3,4-DCPG

CAS NO.：201730-11-2
Empirical Formula: C10H9NO6
Molecular Weight: 239.18
MDL number: MFCD03453633
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-28 23:16:16

What is (S)-3,4-DCPG?

The Uses of (S)-3,4-DCPG

(S)-3,4-DCPG is a potent and selective mGluR-8a agonist.

What are the applications of Application

(S)-3,4-DCPG is a potent and selective mGluR-8a agonist

Biological Activity

Potent, selective mGlu 8a agonist (EC 50 = 31 nM). Displays > 100-fold selectivity over mGlu 1-7 and displays little or no activity at NMDA and kainate receptors. Increases c-Fos expression in stress-related brain areas following systemic administration in mice in vivo . Also potent anticonvulsant in mice in vivo .

storage

Desiccate at RT

Properties of (S)-3,4-DCPG

Boiling point:	531.0±50.0 °C(Predicted)
Density	1.634±0.06 g/cm3(Predicted)
storage temp.	Desiccate at RT
solubility	DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 33 mg/ml; PBS (pH 7.2): 10 mg/ml
pka	1.59±0.10(Predicted)
form	Powder
color	White to off-white
Water Solubility	Soluble to 100 mM in water
InChI	InChI=1S/C10H9NO6/c11-7(10(16)17)4-1-2-5(8(12)13)6(3-4)9(14)15/h1-3,7H,11H2,(H,12,13)(H,14,15)(H,16,17)/t7-/m0/s1

Safety information for (S)-3,4-DCPG

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P330:Rinse mouth. P363:Wash contaminated clothing before reuse. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P501:Dispose of contents/container to..…