(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
Synonym(s):S1P1 Control Molecule
- CAS NO.:909725-64-0
- Empirical Formula: C18H28F3N2O6P
- Molecular Weight: 456.4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-21 10:59:17
What is (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)?
Description
W140 is the inactive enantiomer of the sphingosine-1-phosphate receptor 1 (S1P1) antagonist W146 .1 It only weakly binds to S1P1 (Ki = 4.6 μM for the human receptor). W140 has been used as a negative control in vitro and in vivo in the study of S1P1 signaling.1,2
References
1. Sanna, M.G., Wang, S.K., Gonzalez-Cabrera, P.J., et al. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo Nat. Chem. Biol. 2(8),434-441(2006).
2. Li, C., Chi, X.X., Xie, W., et al. Sphingosine 1-
Properties of (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
storage temp. | Store at -20°C |
solubility | Ethanol: 0.15 mg/ml |
form | A crystalline solid |
Safety information for (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
Computed Descriptors for (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Rimegepant Impurity 3 Ivermectin EP Impurity B (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin B (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin M Tubulysin I Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Calcium Sodium Phosphosilicate IH Imeglimin Hydrochloride IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Methyl 4-amino-3-(4-phenylpiperazin-1-yl)benzoate 3-Morpholino-5,6-dihydropyridin-2(1H)-one 2-(4-Bromopyridin-2-yl)acetonitrile (1-Isopropyl-1H-pyrazol-5-yl)boronic acid 4-Bromo-N,N-bis(4-iodophenyl)aniline 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 3-Fluro-6,7-dihydro-5H-Pyrrolo [3,4-b]pyridine dihydro chloride 4-bromo-7H-pyrrolo[2,3-d]pyrimidineRelated products of tetrahydrofuran
[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
W123 Exclusive
W-5 HYDROCHLORIDE
N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE
BenzenesulfonaMide, 4-chloro-N-[1-(2-phenylethyl)-2-piperidinylidene]-
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