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HomeProduct name listRUBRATOXINA

RUBRATOXINA

RUBRATOXINA Structural

What is RUBRATOXINA?

Description

Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 μM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.

The Uses of RUBRATOXINA

Rubratoxin A is a potent and selective competitive PP2A inhibitor.

What are the applications of Application

Rubratoxin A is a potent and selective competitive PP2A inhibitor

storage

-20°C

Properties of RUBRATOXINA

Melting point: 210-214℃ (decomposition)
storage temp.  Store at -20°C
solubility  Acetonitrile: soluble; DMSO: soluble
form  A powder
color  White

Safety information for RUBRATOXINA

Computed Descriptors for RUBRATOXINA

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