RUBRATOXINA
- CAS NO.：22467-31-8
- Empirical Formula: C26H32O11
- Molecular Weight: 520.528
- MDL number: MFCD01735286
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is RUBRATOXINA?
Description
Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 μM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.
The Uses of RUBRATOXINA
Rubratoxin A is a potent and selective competitive PP2A inhibitor.
What are the applications of Application
Rubratoxin A is a potent and selective competitive PP2A inhibitor
storage
-20°C
Properties of RUBRATOXINA
| Melting point: | 210-214℃ (decomposition) |
| storage temp. | Store at -20°C |
| solubility | Acetonitrile: soluble; DMSO: soluble |
| form | A powder |
| color | White |
Safety information for RUBRATOXINA
Computed Descriptors for RUBRATOXINA
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