rel-(1R,4E,pR)-Cyclooct-4-enol

Synonym(s):(4E)-4-Cycloocten-1-ol;trans-Cyclooctenol;rel-(1R,4E,pR)-Cyclooct-4-enol;TCO-OH

CAS NO.：85081-69-2
Empirical Formula: C8H14O
Molecular Weight: 126.2
MDL number: MFCD24386370
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

rel-(1R,4E,pR)-Cyclooct-4-enol Structural

What is rel-(1R,4E,pR)-Cyclooct-4-enol?

Description

TCO-OH is a TCO intermediate allowed for further derivatizion

The Uses of rel-(1R,4E,pR)-Cyclooct-4-enol

Hydroxyl modified cyclooctene derivative. Cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1,2,4,5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.

Properties of rel-(1R,4E,pR)-Cyclooct-4-enol

Boiling point:	202.2±29.0 °C(Predicted)
Density	0.954±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO
pka	15.13±0.20(Predicted)
form	Liquid
color	Colorless to light yellow

Safety information for rel-(1R,4E,pR)-Cyclooct-4-enol

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H318:Serious eye damage/eye irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for rel-(1R,4E,pR)-Cyclooct-4-enol

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