(R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE
- CAS NO.:75614-87-8
- Empirical Formula: C6H11N3
- Molecular Weight: 125.17
- MDL number: MFCD00209886
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is (R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE?
Chemical properties
White to off-white solid
The Uses of (R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE
R(-)-alpha-Methylhistamine is a potent agonist of the histamine H3-receptor.
Definition
ChEBI: An aralkylamino compound that is histamine bearing a methyl substituent at the alpha-position (the R-enantiomer).
Biological Activity
Very potent, high affinity H 3?agonist (K D = 50.3 nM) that displays > 200-fold selectivity over H 4 receptors. Inhibits H 3 -mediated histamine synthesis and release in the CNS and stimulates H 4 -mediated eosinophil shape change (EC 50 = 66 nM). Also available as part of the Histamine H 3 Receptor Tocriset™ .
Properties of (R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE
Density | 1.094 |
storage temp. | Desiccate at RT |
solubility | H2O: soluble |
form | solid |
color | white to off-white |
Safety information for (R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE
Computed Descriptors for (R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
L-HIS-LEU-LEU-VAL-PHE METHYL ESTER DIHCL
H-PHE-HIS-OME 2 HCL
NA-BENZYL-L-HISTIDINE METHYL ESTERDIHYDR OCHLORIDE
(S)-4,5,6,7-Tetrahydro-3-phenylmethyl-3H-imidazo[4,5-c]pyridine-6-carboxylic acid dihydrochloride
H-HIS(BZL)-OME 2 HCL
PTH-HISTIDINE 2HCL H2O
LABOTEST-BB LT00455302
Methyl L-histidinate dihydrochloride
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