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HomeProduct name list(R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE

(R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE

Synonym(s):D-α,β-Isopropylideneglycerol-γ-tosylate;1,2-Isopropylidene-sn-glycerol 3-tosylate

(R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE Structural

What is (R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE?

Chemical properties

clear yellow to light brown viscous liquid

The Uses of (R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE

(R)-(-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate is a chiral building block. It is used to prepare the antifungal agent ketoconazole. It is also used to prepare acyclic Nucleotide Analogs Derived from 8-Azapurines with antiviral activities.

Properties of (R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE

Melting point: 41-43 °C(lit.)
Boiling point: 398.71°C (rough estimate)
Density  1.208 g/mL at 25 °C(lit.)
refractive index  n20/D 1.506(lit.)
Flash point: >230 °F
storage temp.  -20°C
solubility  Dichloromethane; Chloroform; Ethyl Acetate; Methanol; DMF;
form  Oil
color  Pale Brown
optical activity [α]/D 7.0±0.5°, neat
BRN  89800
CAS DataBase Reference 23788-74-1(CAS DataBase Reference)

Safety information for (R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for (R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE

InChIKey SRKDUHUULIWXFT-LLVKDONJSA-N

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