(R)-(-)-2-Amino-1-butanol

CAS NO.：5856-63-3
Empirical Formula: C4H11NO
Molecular Weight: 89.14
MDL number: MFCD00064419
EINECS: 227-476-4
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

What is (R)-(-)-2-Amino-1-butanol?

Chemical properties

clear colorless to light yellow viscous liquid

Purification Methods

They are purified by shaking with solid NaOH, filtering and distilling through a short column. The oxalate of the racemate has m 176o. They are strong bases and should be stored under N2 in the absence of CO2. The enantiomers have [] 20 ±12.5o (c 2, EtOH). [Johnson & Degering J Org Chem 8 7 1943, Nagao et al. J Org Chem 51 2392 1986, Santaniello et al. J Chem Soc, Perkin Trans 1 919 1985, Beilstein 4 H 291, 4 IV 1705.]

Properties of (R)-(-)-2-Amino-1-butanol

Melting point:	-2 °C
Boiling point:	172-174 °C(lit.)
alpha	-10°(19℃, neat)
Density	0.943 g/mL at 20 °C(lit.)
refractive index	n20/D 1.452
Flash point:	180 °F
storage temp.	Keep in dark place,Sealed in dry,2-8°C
Water Solubility	Soluble in water
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Powder, Crystals and/or Chunks
pka	12.88±0.10(Predicted)
Specific Gravity	0.947
color	White to off-white
PH	11.1 (8.9g/l, H2O, 20℃)
optical activity	[α]19/D 10°, neat
Sensitive	Air Sensitive & Hygroscopic
BRN	1718929
CAS DataBase Reference	5856-63-3(CAS DataBase Reference)
EPA Substance Registry System	(R)-2-Amino-1-butanol (5856-63-3)

Safety information for (R)-(-)-2-Amino-1-butanol

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.