QUINUCLIDINE
Synonym(s):1-Azabicyclo[2.2.2]octane;ABCO
- CAS NO.：100-76-5
- Empirical Formula: C7H13N
- Molecular Weight: 111.18
- MDL number: MFCD00006690
- EINECS: 202-887-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:57
What is QUINUCLIDINE?
The Uses of QUINUCLIDINE
Quinuclidine acts as a catalyst, a chemical building block and is used in organic synthesis. It is employed to prepare quinine and alkaloids. It finds application as a ligand, which is useful in the studies of OsO4-catalyzed dihydroxylation of olefins. It plays an important role in the formation of onium salts used testing of PAC-antagonist activity.
Definition
ChEBI: Quinuclidine is a saturated organic heterobicyclic parent and a member of quinuclidines.
Hazard
A poison by ingestion and skin contact. Low toxicity by inhalation. A moderate skin and severe eye irritant.
Purification Methods
Crystallise it from diethyl ether. The hydrochloride has m 364-365o(dec) (from EtOH or n-BuOH), and the picrate has m 225o (from aqueous EtOH). [Beilstein 20 H 144, 20 II 71, 20 III/IV 1966, 20/4 V 335.]
Properties of QUINUCLIDINE
| Melting point: | 157-160 °C (lit.) |
| Boiling point: | 198.35°C (rough estimate) |
| Density | 0.8928 (rough estimate) |
| vapor pressure | 1.5 mm Hg ( 20 °C) |
| refractive index | 1.4500 (estimate) |
| solubility | H2O: very slightly soluble |
| form | powder to crystal |
| pka | 10.87±0.33(Predicted) |
| color | White to Light yellow |
| Water Solubility | Soluble in alcohol, diethyl ether, water and organic solvents. |
| Sensitive | Air Sensitive |
| Merck | 14,8081 |
| BRN | 103111 |
| CAS DataBase Reference | 100-76-5(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Azabicyclo[2.2.2]octane (100-76-5) |
Safety information for QUINUCLIDINE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H310:Acute toxicity,dermal H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P262:Do not get in eyes, on skin, or on clothing. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for QUINUCLIDINE
| InChIKey | SBYHFKPVCBCYGV-UHFFFAOYSA-N |
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 4-Hydrazinobenzoic acid 3,4-Dibenzyloxybenzaldehyde 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) 4-HYDROXY BENZYL ALCOHOL 3-NITRO-2-METHYL ANILINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 4-methoxy-3,5-dinitropyridine 2-(Cyanocyclohexyl)acetic acid 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride tert-butyl 4- (ureidomethyl)benzylcarbamate diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![3-[(2-Chloro-9H-thioxanthen-9-ylidene)methyl]quinuclidine](https://img.chemicalbook.in/CAS/GIF/36471-39-3.gif)
You may like
-
Quinuclidine CAS 100-76-5View Details
100-76-5 -
Quinuclidine, 97% CAS 100-76-5View Details
100-76-5 -
Quinuclidine CAS 100-76-5View Details
100-76-5 -
55441-95-7 99%View Details
55441-95-7 -
N-Vinylformamide 99%View Details
13162-05-5 -
Chloro Uracil 1820-81-1 99%View Details
1820-81-1 -
2-ethyl-6-methyl-3-hydroxypyridine succinate 99%View Details
127464-43-1 -
2-ETHYLPYRIDINE 100-71-0 99%View Details
100-71-0
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.