PSI-7976
- CAS NO.:1190308-01-0
- Empirical Formula: C22H29FN3O9P
- Molecular Weight: 529.45
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:12
What is PSI-7976?
The Uses of PSI-7976
Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Properties of PSI-7976
Melting point: | 76-82°C |
Density | 1.41±0.1 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly) |
form | Solid |
pka | 9.39±0.10(Predicted) |
color | White to Off-White |
Safety information for PSI-7976
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PSI-7976
Abamectin manufacturer
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GAMMA-CYHALOTHRIN
Sofosbuvir Impurity O
sofosBuvir Impurity 34
SofosBuvir Impurity 2
sofosBuvir Impurity 33
Sofosbuvir metabolites
SofosBuvir Impurity 31
Sofosbuvir impurity D
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