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HomeProduct name listPSEUDOLARIC ACID B

PSEUDOLARIC ACID B

Synonym(s):(-)-Pseudolaric acid B;O-Acetylpseudolaric acid C;Pseudolarix acid B

  • CAS NO.:82508-31-4
  • Empirical Formula: C23H28O8
  • Molecular Weight: 432.46
  • MDL number: MFCD01746346
  • EINECS: 231-291-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
PSEUDOLARIC ACID B Structural

What is PSEUDOLARIC ACID B?

Description

Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of P. kaempferi, a traditional Chinese medicinal plant. It has reported antifungal activities, consistent with its traditional use in the treatment of dermatological fungal infections. Moreover, PAB has diverse effects that are relevant to cancer therapy, including inducing apoptosis of cancer cells (IC50 = ~1 μM), preventing angiogenesis, and inhibiting tumor growth in vivo.

The Uses of PSEUDOLARIC ACID B

(-)-Pseudolaric Acid B is a diterpenoid posessing an immunomodulatory effect. It acts as an immunosuppressant in vitro/vivo however does show some cytotoxicity. Anti-tumor agent as well.

What are the applications of Application

Pseudolaric acid B is a PPARα and PLC activator

Definition

ChEBI: Pseudolaric acid B is a diterpene lactone.

Properties of PSEUDOLARIC ACID B

Melting point: 166°C
Boiling point: 466.14°C (rough estimate)
Density  1.2108 (rough estimate)
refractive index  1.4480 (estimate)
storage temp.  2-8°C
solubility  methanol: soluble1mg/mL, clear, colorless
pka 4.52±0.19(Predicted)
form  powder or crystals
color  white to off-white

Safety information for PSEUDOLARIC ACID B

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
GHS Hazard Statements H301:Acute toxicity,oral
Precautionary Statement Codes P201:Obtain special instructions before use.

Computed Descriptors for PSEUDOLARIC ACID B

InChIKey VDGOFNMYZYBUDT-YCONPBHISA-N

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