PSEUDOLARIC ACID B
Synonym(s):(-)-Pseudolaric acid B;O-Acetylpseudolaric acid C;Pseudolarix acid B
- CAS NO.：82508-31-4
- Empirical Formula: C23H28O8
- Molecular Weight: 432.46
- MDL number: MFCD01746346
- EINECS: 231-291-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-09 19:38:33
What is PSEUDOLARIC ACID B?
Description
Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of P. kaempferi, a traditional Chinese medicinal plant. It has reported antifungal activities, consistent with its traditional use in the treatment of dermatological fungal infections. Moreover, PAB has diverse effects that are relevant to cancer therapy, including inducing apoptosis of cancer cells (IC50 = ~1 μM), preventing angiogenesis, and inhibiting tumor growth in vivo.
The Uses of PSEUDOLARIC ACID B
(-)-Pseudolaric Acid B is a diterpenoid posessing an immunomodulatory effect. It acts as an immunosuppressant in vitro/vivo however does show some cytotoxicity. Anti-tumor agent as well.
What are the applications of Application
Pseudolaric acid B is a PPARα and PLC activator
Definition
ChEBI: Pseudolaric acid B is a diterpene lactone.
Properties of PSEUDOLARIC ACID B
| Melting point: | 166°C |
| Boiling point: | 466.14°C (rough estimate) |
| Density | 1.2108 (rough estimate) |
| refractive index | 1.4480 (estimate) |
| storage temp. | 2-8°C |
| solubility | methanol: soluble1mg/mL, clear, colorless |
| pka | 4.52±0.19(Predicted) |
| form | powder or crystals |
| color | white to off-white |
Safety information for PSEUDOLARIC ACID B
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. |
Computed Descriptors for PSEUDOLARIC ACID B
| InChIKey | VDGOFNMYZYBUDT-YCONPBHISA-N |
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
You may like
-
Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid SaltView Details -
Dechloro DesloratadineView Details -
Dehydro DesloratadineView Details -
Edoxaban Impurity 57View Details
2089454-69-1 -
Eltrombopag N-Oxide ImpurityView Details
2734533-17-4 -
Empagliflozin Bromo ImpurityView Details -
Glycopyrronium Bromide EP Impurity IView Details
1404617-94-2 -
Ipratropium EP Impurity BView Details
58073-59-9
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.