proxymetacaine
- CAS NO.：499-67-2
- Empirical Formula: C16H26N2O3
- Molecular Weight: 294.39
- MDL number: MFCD00864455
- EINECS: 2078849
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:39
What is proxymetacaine ?
Chemical properties
Crystalline Solid
The Uses of proxymetacaine
Topical anesthetic (ophthalmic)
Background
Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
Indications
Used as a local (ophthalmic) anesthetic.
Definition
ChEBI: Proparacaine is a benzoate ester.
brand name
Alcaine (Alcon); Ophthetic (Allergan); Paracaine (Optopics).
Pharmacokinetics
Proparacaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. More specifically, proparacaine appears to bind or antagonize the function of voltage gated sodium channels.
Metabolism
Plasma
Properties of proxymetacaine
| Melting point: | 182-183.30C |
| Boiling point: | 434.4±35.0 °C(Predicted) |
| Density | 1.065 |
| storage temp. | Refrigerator |
| pka | 9.20±0.25(Predicted) |
Safety information for proxymetacaine
Computed Descriptors for proxymetacaine
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