PROTOVERATRINE A
- CAS NO.:143-57-7
- Empirical Formula: C41H63NO14
- Molecular Weight: 793.94
- MDL number: MFCD00135586
- EINECS: 205-602-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:22
What is PROTOVERATRINE A?
Description
A further alkaloid isolated from Veratrum album, this base yields colourless crystals from EtOH. It is laevorotatory with [α]27D - 44.1° (pyridine) or - 12.1° (CHC13). Like the preceding base, it dissolves in H2S04 to give a blue colour. The complex with maleic acid has been prepared as colourless crystals, m.p. 241.5°C; [α]20D - 37.6°. On alkaline hydrolysis, the alkaloid furnishes protoverine, two moles of acetic acid, one mole of (-)-methylbutyric acid and one mole of (+)-2-hydroxy-2-methylbutyric acid.
The Uses of PROTOVERATRINE A
Protoveratrine A is a pharmacological agent which displays neuroprotective effects in ischemic stroke.
Definition
ChEBI: Protoveratrine A is an alkaloid.
brand name
Protalba (Marion Merrell Dow).
References
Stoll, Seebeck., Helv. Chim. Acta, 36,718 (1953)
Properties of PROTOVERATRINE A
Melting point: | 267-269°C |
alpha | D25 -40.5° (pyridine); D25 -10.5° (chloroform) |
Boiling point: | 747.91°C (rough estimate) |
Density | 1.36±0.1 g/cm3 (20 ºC 760 Torr) |
refractive index | 1.6220 (estimate) |
storage temp. | 2-8°C |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | powder |
pka | 10.74±0.70(Predicted) |
color | White |
Safety information for PROTOVERATRINE A
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
Precautionary Statement Codes |
P262:Do not get in eyes, on skin, or on clothing. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for PROTOVERATRINE A
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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