Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listPropionyl-L-carnitine hydrochloride

Propionyl-L-carnitine hydrochloride

Synonym(s):(2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt;L-Carnitine propionyl ester;C3-Carnitine;Propanoyl-L-carnitine

  • CAS NO.:119793-66-7
  • Empirical Formula: C10H20ClNO4
  • Molecular Weight: 253.72
  • MDL number: MFCD00274137
  • EINECS: 922-939-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-09 19:38:33
Propionyl-L-carnitine hydrochloride Structural

What is Propionyl-L-carnitine hydrochloride?

Description

Propionyl-L-carnitine is a naturally occurring carnitine derivative formed by carnitine acetyltransferase during β-oxidation of uneven chain fatty acids. Propionyl-L-carnitine increases the basal release of prostaglandin E2 (PGE2; ) and 6-keto-prostaglandin F in carrageenan-stimulated isolated rat peritoneal cells contaminated with neutrophils and increases the basal release of thromboxane B2 (TXB2; ) in non-contaminated cells. It reduces the production of reactive oxygen species (ROS) and decreases the expression of NADPH oxidase 2 (NOX2), NOX4, and ICAM-1 in human umbilical vein endothelial cells (HUVECs). It also increases the rate of revascularization and the hind limb vascular area in a rabbit model of hind limb ischemia when administered at a dose of 10 mg per animal. Propionyl-L-carnitine reduces mitochondrial dysfunction induced by ischemia, preventing mitochondrial calcium overload, and depletion of ATP tissue stores in a rabbit model of ischemia.

Chemical properties

White Solid

The Uses of Propionyl-L-carnitine hydrochloride

L-Propionyl carnitine has been shown to improve the heart's mechanical recovery and other metabolic parameters after ischemia-reperfusion.

The Uses of Propionyl-L-carnitine hydrochloride

antihypertensive

The Uses of Propionyl-L-carnitine hydrochloride

L-Propionyl carnitine has been shown to improve the heart''s mechanical recovery and other metabolic parameters after ischemia-reperfusion.

What are the applications of Application

(R)-Propionyl Carnitine Chloride is a cardiology reagent

What are the applications of Application

Propionyl L-carnitine hydrochloride is plays a role in mitochondrial metabolism and demonstrates beneficial cardiovascular effects

brand name

Dromos (Biosint S.p.A.).

storage

+4°C

Properties of Propionyl-L-carnitine hydrochloride

Melting point: 165-167°C
storage temp.  Inert atmosphere,Store in freezer, under -20°C
solubility  Chloroform (Slightly), Water (Slightly)
form  Solid
color  White to Off-White
Stability: Hygroscopic
CAS DataBase Reference 119793-66-7(CAS DataBase Reference)

Safety information for Propionyl-L-carnitine hydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for Propionyl-L-carnitine hydrochloride

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.